Camphor toxicity: Difference between revisions
(clinical features) |
(treatment) |
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*Seizure, respiratory depression, coma | *Seizure, respiratory depression, coma | ||
*Hepatitis and liver failure | *Hepatitis and liver failure | ||
==Treatment== | |||
*Aggressive supportive care<ref>American Academy of Pediatrics Policy Statement. Camphor Revisited: Focus on Toxicity (RE9422). Pediatrics 1994;94:127-128</ref> | |||
*Benzodiazepines for seizure | |||
*Intubation and mechanical ventilation as needed | |||
*Charcoal not likely effective | |||
==References== | ==References== | ||
Revision as of 02:12, 22 January 2016
Background
- Common topical agent for pain relief, wart removal, osteoarthritis, cold sores
- FDA limits over the counter preparations to 11%[1]
- Highly lipophilic, widely and rapidly distributed, symptom onset 5-15 minutes
Clinical Features
- Nausea, vomiting, abdominal pain
- Oral burning, headache
- Vertigo, confusion, agitation
- Seizure, respiratory depression, coma
- Hepatitis and liver failure
Treatment
- Aggressive supportive care[2]
- Benzodiazepines for seizure
- Intubation and mechanical ventilation as needed
- Charcoal not likely effective