EBQ:MATTERs Study
Revision as of 23:56, 1 December 2013 by Ostermayer (talk | contribs) (Ostermayer moved page MATTERs to EBQ:MATTERs)
incomplete Journal Club Article
Morrison J. et al. "Military Application of Tranexamic Acid in Trauma Emergency Resuscitation (MATTERs) Study". JAMA Surgery. 2012. 147(2):113-119.
PubMed Full text PDF
PubMed Full text PDF
Clinical Question
Does administration of Tranexamic (TXA) acid in trauma patients with hemorrhage improve mortality in a wartime setting?
Conclusion
The use of TXA with blood component-based resuscitation following combat injury results in improved measures of coagulopathy and survival, a benefit that is most prominent in patients requiring massive transfusion