Hand-foot-and-mouth disease

Background

  • Caused by coxsackie virus
  • Most frequently in children, but can occur in all age groups

Clinical Features

Hand lesions coxsackie virus.
Hand lesions coxsackie virus
Hand lesions coxsackie virus.
Hand lesions coxsackie virus
  • Brief prodrome w/ low fever, anorexia, sore mouth
  • Oral lesions appear 1-2d later
    • Vesicles on erythematous base
    • Painful
  • Hand/foot lesions
    • Red papules that change to gray vesicles

Differential Diagnosis

Workup

Management

  • No specific therapy for most, self-limited
  • Consider Magic Mouthwash if not tolerating PO intake although evidence suggests no better than placebo[1]
  • NSAIDS and cool liquids for pain
  • Encourage good hand hygiene to prevent spread
In infants DO NOT use oral lidocaine due to risk of lidocaine toxicity and FDA black box warning[2]

Disposition

  • Home/Outpatient
  • Resolves after 7–10 days

See Also

Sources

  1. Hopper S. et al. Topical lidocaine to improve oral intake in children with painful infectious mouth ulcers: a blinded, randomized, placebo-controlled trial. Ann Emerg Med. 2014 Mar;63(3):292-9
  2. FDA recommends not using lidocaine to treat teething pain. http://www.fda.gov/Drugs/DrugSafety/ucm402240.htm