Prednisone

General

• Type:
• Dosage Forms:1, 2, 5, 10, 20, 50, 5/5ml
• Common Trade Names: Sterapred, Sterapred DS, Rayos

Adult Dosing

• Corticosteroid-responsive conditions

5-60mg PO qd Dose varies based on condition, best when given with food. Best when given in AM to coincide with natural cortisol release. No need to taper if short course less than 1 week, otherwise consider taper.

• Asthma, acute

40-80 mg/day PO divided qd-bid (most practitioners give 60mg po x 1 to 80-100kg adult) If patient can tolerate PO, no need to give steroids IV, but if asthma is severe, and bipap/intubation likely, best to keep patient NPO and give methylprednisolone

Special Populations

• Pregnancy Rating:
• Lactation:
• Renal Dosing
  • Adult
  • Pediatric
• Hepatic Dosing
  • Adult
  • Pediatric

Contraindications

• Allergy to class/drug

Pharmacology

• Half-life:
• Metabolism:
• Excretion:
• Mechanism of Action: