Geriatric emergency medication safety recommendations

Therapeutic Class Alternatives Exclusions
Barbiturates
  • Epilepsy: use other anticonvulsants (e.g., lamotrigine, levetiracetam).
  • Agitation: treat pain first with acetaminophen then low-dose opioid.
  • Severe agitation: use low-dose second-generation antipsychotic (eg, olanzapine, risperidone, quetiapine [Lewy body dementia]).
  • Seizures disorders, benzodiazepine or ethanol withdrawal, barbiturates are acceptable to use.
Benzodiazepines
  • Epilepsy: use other anticonvulsants (eg, lamotrigine, levetiracetam).
  • Agitation: treat pain first with acetaminophen then low-dose opioid.
    • Severe agitation: use nonpharmacologic approach then low-dose second-generation antipsychotic (eg, olanzapine, risperidone,
      quetiapine [Lewy body dementia]).
  • Seizure disorders: benzodiazepine or ethanol withdrawal, severe generalized anxiety disorder, and end of life, benzodiazepines are acceptable to use.
First-Generation Antihistamines
  • Allergies: use intranasal saline or steroid (eg, fluticasone, beclomethasone), topical antihistamines (eg, azelastine), or second-generation antihistamines (eg, fexofenadine, loratadine).
  • Vertigo: use short-term steroids and canalith repositioning maneuvers.









See Also