Template:Diabetic foot infection antibiotics
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Associated organisms include Staphylococcus, Streptococcus, Enterococcus, Enterobacteriaceae, Proteus, Bacteroides, and Pseudomonas, and Klebsiella
Superficial Mild Infections
- Clindamycin 450mg PO q8h4s daily x 14 days OR
- TMP/SMX 2DS tabs PO q12hrs daily x 14 days OR
- Doxycycline 100mg PO q12hrs daily x 14 days
Prior antibiotic treatment or moderate infections
- Amoxicillin/Clavulanate 875/125mg PO q12hrs + TMP/SMX 2DS tabs PO q12hrs daily x 14 days OR
- Clindamycin 450mg PO q8hrs + Ciprofloxacin 750mg PO q12hrs x 14 days
Inpatient Treatment
- Vancomycin 15-20mg/kg IV q12hrs plus
- Ampicillin/Sulbactam 3g IV q6hrs OR
- Piperacillin/Tazobactam 4.5g IV q8hrs OR
- Ticarcillin/Clavulanate 3.1g IV q8hrs OR
- Imipenem 500mg IV q6hrs OR
- Metronidazole 500mg IV q8hrs PLUS
- Cefepime 2g IV q12hrs OR
- Ciprofloxacin 400mg IV q12hrs OR
- Aztreonam 2g IV q8hrs