Mesenteric panniculitis

Background

  • Also known as "sclerosing mesenteritis"
  • A rare, benign, and chronic fibrosing inflammatory disease that affects the adipose tissue of the mesentery (of the small intestine and colon)[1].
  • Specific cause is unknown[2]

Clinical Features

Differential Diagnosis

Evaluation

  • Regional increase in mesenteric fat density on abdominal CT (i.e. “misty mesentery”)
    • May be confirmed by surgical biopsy

Management

  • Supportive ED treatment
  • Chronic treatment includes workup of underlying etiology and consideration of medical therapy for severe/protracted disease (e.g. corticosteroids, cyclophosphamide, or azathioprine)

Disposition

  • Outpatient

See Also

External Links

References

  1. Issa I and Baydoun H. Mesenteric panniculitis: Various presentations and treatment regimens. World J Gastroenterol. 2009 Aug 14; 15(30): 3827–3830.
  2. Issa I and Baydoun H. Mesenteric panniculitis: Various presentations and treatment regimens. World J Gastroenterol. 2009 Aug 14; 15(30): 3827–3830.