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• 00:36, 28 January 2026 Ostermayer talk contribs created page Loop diuretic (Created page with "== Background == * Mechanism: Inhibits Na-K-2Cl carrier in the '''thick ascending Loop of Henle'''^1^ * Potency: Highest among diuretic classes * '''Adverse Effects''' ** Hypokalemia (most common) ** Hypomagnesemia, hyponatremia, hypocalcemia ** Ototoxicity (associated with rapid IV push) ** Pre-renal AKI (due to over-diuresis) * '''Sulfa Allergy:''' Most are sulfonamide derivatives; cross-reactivity is rare but possible == Key Agents == * '''F...")