Neutropenic enterocolitis

Definition

Necrosis of bowel wall 2/2 microbial invasion

Pathophysiology

1. Usually involves the CECUM
2. Typically occurs 10-14d after cytotoxic therapy

Diagnosis

1. Fever
2. RLQ pain
3. Nausea
4. Vomiting
5. (mimics appy)

Workup

CT A/P: cecal distention and wall thickening

Treatment

1. Bowel rest
2. NG suction
3. IVF
4. Broad spec abx

Disposition

Surgical consultation (right hemicolectomy)

Prognosis

Mortality 50%