Sandbox
Revision as of 09:47, 19 September 2017 by Rossdonaldson1 (talk | contribs)
| TOXIN | ANTIDOTE |
| Acetaminophen | N-Acetylcysteine |
| 150mg/kg IV load over 60min; followed by 50mg/kg IV over 4hr and then 100mg/kg IV over 16hr | |
| Anticholinergics | Physostigmine |
| Arsenic | Dimercaprol (BAL) |
| Benzodiazepines | Flumazenil |
| Adult: 0.2mg IV | |
| Peds: 0.01mg/kg IV | |
| Beta blockers | Glucagon |
| Adult: 3-10mg IV | |
| Peds: 50-150mcg/kg IV | |
| Ca channel blockers | Calcium chloride 10% |
| Adult: 10 mL IV | |
| Peds: 0.2-0.25 mL/kg IV | |
| High Dose Insulin (1 unit/kg/hr) | |
| Clonidine | Naloxone |
| Adult: 0.4-2mg IV | |
| Peds: 0.1mg/kg IV (max 2mg) | |
| Cyanide | Hydroxycobalamin OR Cyanide antidote kit (Amyl Nitrite, Sodium Nitrite, and Sodium Thiosulfate) |
| Digoxin | Dig Immune Fab |
| Ethylene glycol | Fomepizole |
| 15mg/kg IV; then 10mg/kg q12h | |
| Fluoride | Calcium gluconate |
| Heparin | Protamine Sulfate |
| Adult: 25-50mg IV (empiric dose) over 10 minutes | |
| Peds: 0.6mg/kg IV (empiric dose) | |
| Note: Rapid protamine infusion causes hypotension[1] | |
| Iron | Deferoxamine |
| Isoniazid (INH) | Pyridoxine (Vit B6) |
| Adult: 5gm IV | |
| Peds: 1gm/kg regardless of age [2] | |
| Lead | EDTA, succimer |
| Mercury | Dimercaprol (BAL) |
| Methanol | Fomepizole |
| 15mi/kg IV; then 10mg/kg q12h | |
| Methemoglobinemia | Methylene blue |
| Opiods | Naloxone |
| Organophosphates | Atropine + Pralidoxime |
| Sulfonylurea | Octreotide |
| Adult: 50–100mcg SC q6hr | |
| Peds: 1mcg/kg SC q6hr | |
| Tricyclic (TCA) Toxicity | Bicarbonate |
| 1-2mEq/kg IV bolus followed by 2mEq/kg/hr IV infusion | |
| Valproate | L-Carnitine |
| Warfarin | Vitamin K, FFP, Prothrombin complex concentrate |