Digital EpiPen injection

Background

  • Accidental digital self-injection of epinephrine from an EpiPen.

Clinical Features

  • Puncture wound with delayed capillary refill (vasoconstriction)

Differential Diagnosis

Evaluation

  • Typically a clinical diagnosis (no testing required)

Treatment

  • Observation for 2 hours after injection[1]
  • If continued ischemia symptoms after 2 hrs

Injection Procedure[2]

Epinephrine induced digital vasospasm using Phentolamine

Indications

For use when epinephrine is accidentally or inappropriately injected

Contraindications

Drug class allergy or non-ischemia.

Equipment Needed

10cc syringe, phentolamine, 1-2% lidocaine, 25g needle.

Technique

  • Dilute 1.5mg of phentolamine mesilate in 1ml of 2% lidocaine.
  • Inject subQ into the site and stop when tissue turns pink again.
  • Observe and repeat as necessary.

Disposition

  • Outpatient

See Also

References

  1. "Six Years of Epinephrine Digital injections: Absence of Significant Local or Systemic Effects." Annals of EM. Sept. 2010. 56(3):p270-274.
  2. http://emj.bmj.com/content/21/3/387/