Vancomycin
Revision as of 23:06, 27 February 2014 by Rossdonaldson1 (talk | contribs)
General
- Type: 125mg, 250mg
- Dosage Forms:
- IV
- May mix IV with 30mL water and give PO
- May mix with 100mL NS and give PR
- Common Trade Names: Vancocin
Adult Dosing
General
- <50kg: 500mg IV q12h
- 50-69kg: 750mg IV q12h
- >70kg: 1000mg IV q12h
- Alternative (All Weights): 10-15 mg/kg IV q12
- Adjust dose based on serum levels
C. Difficile Infection
- 1st occurrence
- Uncomplicated: 125mg PO q6h x 10-14 days
- Complicated: 500mg PO/NG q6h
- May use in combo with metronidazole IV
- Consider adding vancomycin 500mg PR q6 if complete ileus
- 2nd occurrence
- Uncomplicated: 125mg PO q6h x 10-14 days
- Complicated: 500mg PO/NG q6h
- May use in combo with metronidazole IV
- Consider adding vancomycin 500mg PR q6 if complete ileus
- 3rd+ occurrence
- 125mg PO q6h x 10-14 days, then daily x 7 days, then q2-3 days x 2-8 wk
Staphylococcal Enterocolitis
- 500-2000 mg/day PO divided q6-8h x 7-10 days
- First Dose: 500mg PO x 1
Pediatric Dosing
Special Populations
- Pregnancy:
- Lactation:
- Renal Dosing
- Adult
- Pediatric
- Hepatic Dosing
- Adult
- Pediatric
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
Common
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
- Mechanism of Action:
See Also
Source
- Epocrates