EBQ:Sgarbossa Criteria Study

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incomplete Journal Club Article
Sgarbossa E. et al.. "Electrocardiographic diagnosis of evolving acute myocardial infarction in the presence of left bundle-branch block. GUSTO-1 (Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries) Investigators". NEJM. 1996. 334(8):481-7.
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Clinical Question

How can we Diagnose Acute Myocardial Infarction in Left Bundle Branch Block patients ?

Conclusion

A Validated Clinical prediction rule has been Developed based on ECG criteria to Diagnose Acute Myocardial infarction in Left Bundle Branch Patients

Major Points

  1. ST-segment Elevation of at least 1 mm with concordance with the QRS complex
  2. ST-segment depression in leads V1, V2 or V3
  3. ST-segment Elevation of atleast 5 mm with discordance with the QRS complex

Study Design

Population

Patient Demographics

More males in the experimental group and More Left Axis and more previous MI patients in the control group

Inclusion Criteria

Patients with LBBB

Exclusion Criteria

Interventions

Outcomes

Primary Outcome

Acute Myocardial Infarction

Secondary Outcomes

Subgroup analysis

Criticisms & Further Discussion

Funding

Grant from Bayer, Genentech, CIBA–Corning, ICI Pharmaceuticals, and Sanofi Pharmaceuticals.

Sources