EBQ:Sgarbossa Criteria Study
incomplete Journal Club Article
Sgarbossa E. et al.. "Electrocardiographic diagnosis of evolving acute myocardial infarction in the presence of left bundle-branch block. GUSTO-1 (Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries) Investigators". NEJM. 1996. 334(8):481-7.
PubMed Full text PDF
PubMed Full text PDF
Clinical Question
How can we Diagnose Acute Myocardial Infarction in Left Bundle Branch Block patients ?
Conclusion
A Validated Clinical prediction rule has been Developed based on ECG criteria to Diagnose Acute Myocardial infarction in Left Bundle Branch Patients
Major Points
- ST-segment Elevation of at least 1 mm with concordance with the QRS complex
- ST-segment depression in leads V1, V2 or V3
- ST-segment Elevation of atleast 5 mm with discordance with the QRS complex
Study Design
Population
Patient Demographics
More males in the experimental group and More Left Axis and more previous MI patients in the control group
Inclusion Criteria
Patients with LBBB
Exclusion Criteria
Interventions
Outcomes
Primary Outcome
Acute Myocardial Infarction
Secondary Outcomes
Subgroup analysis
Criticisms & Further Discussion
Funding
Grant from Bayer, Genentech, CIBA–Corning, ICI Pharmaceuticals, and Sanofi Pharmaceuticals.
