Mucositis
Background
- One of the most common side effects of cancer treatment with chemotherapy or radiation
- Occurs in almost all cases of head or neck radiation
- 20-80% of people who receive chemotherapy
Clinical features
- Erythema and ulcerations of the mucosal lining of the gastrointestinal tract
- Causes dysphagia, changes in taste, secondary infections, weight loss
- Oral mucositis is associated with increased inpatient hospitalization duration, bacteremia and higher 100‐day mortality.
- GI mucositis is associated with nausea, vomiting, bloating, diarrhea, intestinal cramping and anal pain.
Differential Diagnosis
- Oral candidiasis
- Herpes simplex virus infection
- Acute Graft-versus-Host disease
Evaluation
Workup
Diagnosis
Management
- Prevention with multi agent, combination oral care[2]
Disposition
See Also
External Links
References
- ↑ Daugėlaitė G, Užkuraitytė K, Jagelavičienė E, Filipauskas A. Prevention and Treatment of Chemotherapy and Radiotherapy Induced Oral Mucositis. Medicina (Kaunas). 2019;55(2):25. Published 2019 Jan 22. doi:10.3390/medicina55020025
- ↑ Elad S, Cheng KKF, Lalla RV, et al. MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy. Cancer. 2020;126(19):4423-4431. doi:10.1002/cncr.33100