Cimetidine

General

• Type: H2 Blocker
• Dosage Forms: 200, 300, 400, 800 mg
• Common Trade Names: Tagamet HB 200

Adult Dosing

Duodenal Ulcer, Active: 800 mg PO QHS x 4-8 weeks

Duodenal Ulcer, Maintenance: 400 mg PO QHS

Gastric Ulcer, active benign: 800 mg PO QHS x 6 weeks

H. Pylori Infection: 400 mg PO BID x 10-28 days

Pediatric Dosing

GERD/PUD:

   * Neonates: 5- 10 mg/kg/day PO divided q8-12h
   * Infants: 10-20 mg/kg/day PO divided q8-12h
   * Children: 20-40 mg/kg/day PO divided q6H

Special Populations

• Pregnancy Rating:
• Lactation:
• Renal Dosing
  • Adult
  • Pediatric
• Hepatic Dosing
  • Adult
  • Pediatric

Contraindications

• Allergy to class/drug

Pharmacology

• Half-life:
• Metabolism:
• Excretion:
• Mechanism of Action: