Hodgkin's lymphoma

Background

• Spreads from source lymph node to adjacent nodes
• Bimodal distribution: young adulthood and older aged
• Most common malignancy between ages of 15-19 yo
• Survival >90% in low-risk pts

Clinical Features

• Painless, firm, lymph node (usually cervical or supraclavicular)
• "B" symptoms: fever, night sweats, wt loss

Differential Diagnosis

Cervical lymphadenopathy

1. Non-Hodgkin lymphoma
2. Mononucleosis
3. Toxoplasmosis
4. Branchial cleft lesions
5. Cat scratch disease
6. Mycobacterial adenitis

Diagnosis

• CXR
• CT neck/C/A/P
• LN biopsy

Treatment

• Manage acute complications
  • Superior vena cava syndrome
  • Upper airway compression
    • Do NOT give steroids

See Also

• Lymphoma
• Oncologic emergencies