Nitrogen tetroxide toxicity

Background

  • N2O4 (NTO) is used as a propellant.
  • In 1975 three astronauts on the Apollo-Soyuz Test Project were exposed to NTO during reetry and treated for pulmonary edema and chemical pneumonitis

Clinical Features

  • Eye burning and tearing
  • Cutaneous pruritis
  • Shortness of breath
  • Cough
  • Pulmonary edema

Evaluation

  • Xray (if available)

Treatment

  • Supportive care after removal from the contaminated environment.


References