Geriatric emergency medication safety recommendations

Therapeutic Class Alternatives Exclusions
Barbiturates
  • Epilepsy: use other anticonvulsants (eg, lamotrigine, levetiracetam).
  • Agitation: treat pain first with acetaminophen then low-dose opioid.
  • Severe agitation: use low-dose second-generation antipsychotic (eg, olanzapine, risperidone, quetiapine [Lewy body dementia]).
For seizures disorders, benzodiazepine or ethanol withdrawal, barbiturates are
acceptable to use.52-56
Benzodiazepines For epilepsy, use other anticonvulsants (eg, lamotrigine,
levetiracetam).46-48 For agitation, treat pain first with
acetaminophen then low-dose opioid.49,74,75 For severe
agitation, use nonpharmacologic approach then low-dose
second-generation antipsychotic (eg, olanzapine, risperidone,
quetiapine [Lewy body dementia]).49
For seizure disorders,
benzodiazepine or ethanol
withdrawal, severe generalized
anxiety disorder, and end of life,
benzodiazepines are acceptable
to use.52-54,57,58









See Also