Template:Thrombocytopenia

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Thrombocytopenia

  • Decreased production
    • Marrow infiltration (tumor or infection)
    • Viral infections (rubella, HIV)
    • Drugs
    • Radiation
    • Vitamin B12 and/or folate deficiency
  • Increased platelet destruction
    • ITP
    • TTP
    • HUS
    • DIC
    • Viral infections (HIV, mumps, varicella, EBV)
    • Drugs (heparin, protamine)
  • Platelet loss
    • Excessive hemorrhage
    • Hemodialysis, extracorporeal circulation
  • Splenic sequestration
    • Sickle cell disease, cirrhosis
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