Herpes Simplex Virus-1

Herpes labialis (cold sore)

Herpes labialis

• typically umbilicated vesicles, painful, that unroof and crust over
• typically localized to the vermillion border

Herpes gingivostomatitis

Herpes gingivostomatitis of mouth

Painful vesicular lesions of mucocutaneous areas

• Primary HSV-1 infection of lips, gingiva, and tongue
• Associated with fevers, irritability, and cervical adenopathy
• Lasts approx 2-4 weeks without treatment, course shortened with treatment
  • Acyclovir 40-80mg/kg PO divided in 3-4 doses for 5-7 days
• PO intake is most important

Herpes keratitis

Herpes keratitis

Eczema herpeticum

• Development of vesicular eruptions in areas of epidermis previously affected by atopic dermatitis
• fever is common
• May be life-threatening
• Treatment to cover Staph and Strep
• Bactrim 10mg/kg/d in 2 divided doses OR clindamycin 24mg/kg/d divided into 3 doses x10d
• Acyclovir 80mg/kg/d in 3 divided doses x10

See Also

• Pediatric Rashes
• Herpes Viruses

Source

Tintinalli