CO2 narcosis

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Background

  • increased CO2 in the blood leading to depressed mental status
  • most commonly seen in acute exacerbations of obstructive pulmonary diseases
  • can also be seen in SCUBA divers

Clinical Features

  • headache, confusion, lethargy, propensity for arrhythmias, seizure/coma/death

Differential Diagnosis

  • drug intoxication
  • encephalopathy (renal, hepatic, hypertensive)
  • ICH
  • seizure

Diagnosis

  • ABG

Management

  • hyperventilation with either NIPPV or intubation/mechanical ventilation depending on severity and patient's mental status

Disposition

  • admission to a monitored setting

See Also

External Links

References

  • 1. Bove, A. (2014). Diving Medicine. Am J Respir Crit Care Med, 189(12), 1479-1486. doi:10.1164/rccm.201309-1662ci
  • 2. Clark, J. (2015). Moving in extreme environments: inert gas narcosis and underwater activities. Extrem Physiol Med, 4(1), 1. doi:10.1186/s13728-014-0020-7
  • 3. Lindholm, P., & Lundgren, C. (2008). The physiology and pathophysiology of human breath-hold diving. Journal Of Applied Physiology, 106(1), 284-292. doi:10.1152/japplphysiol.90991.2008
  • 4. Hypercapnia. (n.d.). In Wikipedia. Retrieved January 11, 2016, from http://en.wikipedia.org/wiki/hypercapnia