Camphor toxicity

Revision as of 02:05, 22 January 2016 by Kian (talk | contribs) (clinical features)

Background

  • Common topical agent for pain relief, wart removal, osteoarthritis, cold sores
  • FDA limits over the counter preparations to 11%[1]
  • Highly lipophilic, widely and rapidly distributed, symptom onset 5-15 minutes

Clinical Features

  • Nausea, vomiting, abdominal pain
  • Oral burning, headache
  • Vertigo, confusion, agitation
  • Seizure, respiratory depression, coma
  • Hepatitis and liver failure

References

  1. ↑ United States Food and Drug Administration. Proposed rules: external analgesic drug products for over-the-counter human use; tentative final monograph. Fed Reg 1983
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