Neuroblastoma (peds)
Revision as of 15:59, 22 March 2016 by Ostermayer (talk | contribs) (Text replacement - "Category:Peds" to "Category:Pediatrics")
Background
- Arises from primitive ganglion cells of sympathetic nervous system
- Most common neoplasm in 1st yr of life
- May arise anywhere along sympathetic nervous system
- Adrenal gland (40%)
- Abdomen (25%)
- Chest (15%)
Clinical Features
- Depends on location
- Large, painless abdominal mass
- Compression of bowel/bladder
- Horner syndrome
- Spinal cord compression
- Opsoclonus-myoclonus
- Highly a/w neuroblastoma
- Neutropenia/pancytopenia suggests bone marrow involvement
Differential Diagnosis
Diagnosis
- CXR
Management
- Admssion for tumor biopsy