Streptococcal pharyngitis

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Background

  • Strep pharyngitis
    • Peak in 5-15yr old
    • Rare in <2yr of age
    • Accounts for only 15-30% of pharyngitis

DDx

  1. Viral pharyngitis
  2. PTA
  3. Retropharyngeal abscess
  4. EBV pharyngitis
  5. CMV pharyngitis
  6. Gonococcal pharyngitis

Diagnosis

Clinical Features

  • Sore throat
  • Painful swallowing
  • Fever
  • N/V
  • Tonsillar exudate

Centor Criteria

  1. History of fever
  2. Absence of cough
  3. Lymphadenopathy
  4. Tonsillar exudate

Treatment

Treatment Algorithm by Centor Criteria

Points
Treatment
4
Rx without testing
3
Rapid Strep Test
2
Rapid Strep Test
1
Do not test/treat
0
Do not test/treat
  • Likelihood of streptococcal pharyngitis in pts presenting with sore throat
    • 4 criteria = 50% PPV
    • 3 criteria = 40% PPV
    • 0 criteria - 80% NPV

=Treatment Medications

  • Abx
    • Tx can be delayed for up to 9 days and still prevent major sequelae
    • Choices
      • Penicillin
        • 250mg BID x 10d (child) or 500mg BID x 10d (adolescent)
      • Bicillin
        • 25-50Kmg/kg IM x 1 (max dose = 1.2million)
      • Azithromycin (penicillin allergic)
        • 12mg/kg QD (child) or 500mg on day 1; then 250mg on days 2-5
  • Steroids
    • Single dose of dexamethasone shortens duration of pain

See Also

Source

  • Tintinalli
  • Rosen's