Non-Hodgkin's lymphoma

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Background

  • May originate in lymphatic system or any organ in the body
  • Occurs in children >5yr old
  • Risk factors
    • Immunosuppression (HIV, Crohn, chemo recipients)

Clinical Features

  • Lymphadenopathy
  • Hepatosplenomegaly
  • "B" symptoms
  • GI
    • Bleeding, intussusception, N/V

Differential Diagnosis

Cervical Lymphadenopathy

Acute Leukemia/Lymphoma

Diagnosis

  • CBC
  • Chemistry
  • Uric acid
  • LFT
  • CXR

Management

Complications

  • Superior vena cava syndrome
  • Pleural/pericardial effusions
  • Spinal cord compression

See Also

References