CHF medications

Agent	RA	RCW	SVR	BP	CO
Isordil60	-	-	(-)	-	-+
hydral100	~	~	-	+-	++
hy (MR/AI)	-	--	++	-+	+-
ACEI	-	-	-	+-	+
Minoxidil	~	~	--	+-	++

Carvedilol: decreases mortality 67%

Digoxin: decrease syx/hospitaliz.

Aldactone in Class IV dec mortality

Isordil: cor. VD; +BP if ischemia

ISDN/HYDRA. decreased mortality in CHF.

ACEI GREAT mortality benefit.

Target Doses

Hydralazine: 100 TID start 25

Isordil: 60-80 TID

Captopril: 100 TID start 12.5

Lisinopril/enalapril: 10 bid class II/III

20 bid class IV

Carvedilol 25 BID; 50 BID if >80kg

Digoxin: varies

Spironolactone 25-50 qd

Enalapril 1.25mg IV

Nitroglycerin (Initial dose 5-10ug/min, increased every 3-5 minute to dose range 10-200ug/min)

Nitroprusside (Initial dose 5-10ug/min, increased every 3-5 minute to dose range 5-400ug/min)

• Consider when need afterload reduction

See Also

Cards: Congestive Heart Failure (CHF)