Acute necrotizing ulcerative gingivitis: Difference between revisions

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==Background==
==Background==
*Also known as "trench mouth"
*Often abbreviated as ''ANUG''
*Often abbreviated as ''ANUG''
*Some literature equates as the same as [[Vincent's angina]], and other literature suggests ANUG and [[Vincent's angina]] are different
*Severe gingival disease that may spread to local soft tissue and bone
*Severe gingival disease that may spread to local soft tissue and bone
*Must distinguish from [[Herpes gingivostomatitis]]
*Must distinguish from [[Herpes gingivostomatitis]]
*Bacteria involved: anaerobic fusobacterium and ''Borellia spirochete''<ref>J Periodontol. 1986 Mar;57(3):141-50. Acute necrotizing ulcerative gingivitis. A review of diagnosis, etiology and treatment. Johnson BD, Engel D.</ref>
**Herpes has more systemic signs, less bleeding, lack of interdental papilla involvement
**Herpes has more systemic signs, less bleeding, lack of interdental papilla involvement
*Associated with <ref>J Periodontol. 1986 Mar;57(3):141-50. Acute necrotizing ulcerative gingivitis. A review of diagnosis, etiology and treatment. Johnson BD, Engel D.</ref>
*Bacteria involved: anaerobic fusobacterium and ''Borellia spirochete''<ref>J Periodontol. 1986 Mar;57(3):141-50. Acute necrotizing ulcerative gingivitis. A review of diagnosis, etiology and treatment. Johnson BD, Engel D.</ref>, Treponema, Selenomonas, Prevotella
**Immunosuppression, especially HIV
*[[Vincent's angina]] is sometimes confused with [[ANUG]], but the former is tonsillitis and pharyngitis, and the latter involves the gums
**Poor oral hygiene/nutrition/sleep
 
**Stress
===Associated Conditions<ref>J Periodontol. 1986 Mar;57(3):141-50. Acute necrotizing ulcerative gingivitis. A review of diagnosis, etiology and treatment. Johnson BD, Engel D.</ref>===
**ETOH/tobacco use
*Immunosuppression, especially [[HIV]]
**Age<21
*Poor oral hygiene/nutrition/sleep
**Caucasians
*Stress
**malaria/measles/parasites
*[[ETOH]]/tobacco use
*Age<21
*Caucasians
*[[malaria]]/[[measles]]/[[parasites]]


==Clinical Features==
==Clinical Features==
[[File:Ulcerative necrotizing gingivitis.jpg|thumb|Mild presentation at the typical site on the gums of the lower front teeth.]]
[[File:Ulcerative necrotizing gingivitis.jpg|thumb|Mild presentation at the typical site on the gums of the lower front teeth.]]
*Early:
===Early===
**Fever
*[[Fever]]
**Halitosis
*Halitosis
**Pain
*[[dental problems|Dental/mouth pain]]
**Gingival bleeding
*Gingival bleeding
**Teeth mobility
*Teeth mobility
**Malaise
*Malaise
*Secondary signs:
 
**Fetid breath with metallic taste
===Secondary signs===
**"Wooden teeth" feeling
*Fetid breath with metallic taste
**Regional lymphadenopathy
*"Wooden teeth" feeling
**Ulcerated, with grayish pseudomembrane or "punched out" interdental papillae
*Regional [[lymphadenopathy]]
*Ulcerated, with grayish pseudomembrane or "punched out" interdental papillae
*Blunting of the typically pointed edges of the papillae


==Differential Diagnosis==
==Differential Diagnosis==
{{Template:Dental Problems DDX}}
{{Dental Problems DDX}}


==Diagnosis==
==Evaluation==
*Usually clinical
*Usually clinical


==Management==
==Management==
*Organisms involved are polymycrobial but often include Fusobacterium necrophorum, Treponema spp, Selenomonas, and Prevotella
{{ANUG Treatment}}
 
'''Uncomplicated Disease'''
*Antibiotics
**Amoxicillin, 250 mg 3 x daily for 7 days and/or
**Metronidazole, 250 mg 3 x daily for 7 days<ref>Atout R. N. et al.  Managing Patients with Necrotizing Ulcerative Gingivitis. J Can Dent Assoc 2013;79:d46.  http://www.jcda.ca/article/d46. Accessed April 2015</ref>
 
 
'''Complicated Disease'''
*Antibiotics
**Penicillin V 500 mg PO q6 hours AND Metronidazole 500mg PO q8 hours x 10 days '''or'''
**Amoxicillin 500 mg PO TID for 10d plus metronidazole 250 mg PO TID for 10d '''or'''
**Amoxicillin-clavulanate 500 mg/125mg PO TID or 875mg/125mg PO BID for 10d '''or'''
**Clindamycin 150-300 mg PO TID for 10d '''or'''
**Doxycycline 100 mg PO BID for 10d<ref>Stephen J. et al Acute Necrotizing Ulcerative Gingivitis Empiric Therapy. http://emedicine.medscape.com/article/2028117-overview. Accessed April 2015</ref>
 
 
'''Additional'''
*Oral Treatment
**Chlorhexidine 0.01% oral rinse BID
**Hydrogen peroxide swishing (cheap home remedy)
*Pain
**Ibuprofen 400-600 mg 3 times daily
**Mouth cocktail Rx - 300cc of 1:1:1 viscous lidocaine 2%, Maalox, diphenhydramine 12.5mg/5ml elixir
*HIV+
**In addition to antibiotic regimen consider an oral anti-fungal or nystatin
**Fluconazole 200mg PO daily for 14 days
 


===Consultation===
===Consultation===
ENT or OMFS consult for dental debridement may be required in severe infections
ENT or OMFS consult for dental debridement may be required in severe infections
==Disposition==
Discharge


==See Also==
==See Also==
*[[Dental Problems]]
*[[Dental problems]]


==References==
==References==
<references/>
<references/>
*ER Atlas


[[Category:ENT]]
[[Category:ENT]]
[[Category:ID]]
[[Category:ID]]

Revision as of 21:58, 3 February 2020

Background

  • Also known as "trench mouth"
  • Often abbreviated as ANUG
  • Some literature equates as the same as Vincent's angina, and other literature suggests ANUG and Vincent's angina are different
  • Severe gingival disease that may spread to local soft tissue and bone
  • Must distinguish from Herpes gingivostomatitis
    • Herpes has more systemic signs, less bleeding, lack of interdental papilla involvement
  • Bacteria involved: anaerobic fusobacterium and Borellia spirochete[1], Treponema, Selenomonas, Prevotella
  • Vincent's angina is sometimes confused with ANUG, but the former is tonsillitis and pharyngitis, and the latter involves the gums

Associated Conditions[2]

Clinical Features

Mild presentation at the typical site on the gums of the lower front teeth.

Early

Secondary signs

  • Fetid breath with metallic taste
  • "Wooden teeth" feeling
  • Regional lymphadenopathy
  • Ulcerated, with grayish pseudomembrane or "punched out" interdental papillae
  • Blunting of the typically pointed edges of the papillae

Differential Diagnosis

Dentoalveolar Injuries

Odontogenic Infections

Other

Evaluation

  • Usually clinical

Management

Organisms involved are polymycrobial but often include Fusobacterium necrophorum, Treponema spp, Selenomonas, and Prevotella

Uncomplicated Disease

Additional Therapies for the immunocompromised

For patient with AIDS or immunocompromised with risk of oral candidal infection then add:

Additional Therapies for all patients

  • Chlorhexidine 0.01% oral rinse BID
  • Hydrogen peroxide swishing (innexpensive home remedy)
  • Ibuprofen 400-600mg 3 times daily for pain
    • Magic Mouthwash (multiple variations) - 300cc of 1:1:1 viscous lidocaine 2%, Maalox, diphenhydramine 12.5mg/5ml elixir

Consultation

ENT or OMFS consult for dental debridement may be required in severe infections

Disposition

Discharge

See Also

References

  1. J Periodontol. 1986 Mar;57(3):141-50. Acute necrotizing ulcerative gingivitis. A review of diagnosis, etiology and treatment. Johnson BD, Engel D.
  2. J Periodontol. 1986 Mar;57(3):141-50. Acute necrotizing ulcerative gingivitis. A review of diagnosis, etiology and treatment. Johnson BD, Engel D.
  3. Atout R. N. et al. Managing Patients with Necrotizing Ulcerative Gingivitis. J Can Dent Assoc 2013;79:d46. http://www.jcda.ca/article/d46. Accessed April 2015
  4. Walker C. et al. Rationale for use of antibiotics in periodontics. J Periodontol. 2002. 73(1):1188-96