Acute necrotizing ulcerative gingivitis: Difference between revisions

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==Treatment==
==Treatment==
{{ANUG Antibiotics}}
*Organisms involved are polymycrobial but often include Fusobacterium necrophorum, Treponema spp, Selenomonas, and Prevotella
 
*Chlorhexidine 0.01% oral rinse BID
*Chlorhexidine 0.01% oral rinse BID
*Hydrogen peroxide swishing (cheap home remedy)
*Hydrogen peroxide swishing (cheap home remedy)

Revision as of 21:50, 22 April 2015

Background

  • Often abbreviated as ANUG
  • Severe gingival disease that may spread to local soft tissue and bone
  • Must distinguish from Herpes gingivostomatitis
  • Bacteria involved: anaerobic fusobacterium and Borellia spirochete[1]
    • Herpes has more systemic signs, less bleeding, lack of interdental papilla involvement
  • Associated with [2]
    • Immunosuppression, especially HIV
    • Poor oral hygiene/nutrition/sleep
    • Stress
    • ETOH/tobacco use
    • Age<21
    • Caucasians
    • malaria/measles/parasites

Clinical Features

Mild presentation at the typical site on the gums of the lower front teeth.
  • Triad of:
    • Fever
    • Pain
    • Regional lymphadenopathy
    • Ulcerated, with grayish pseudomembrane or "punched out" interdental papillae
    • Gingival bleeding
  • Secondary signs:
    • Fetid breath with metallic taste
    • "Wooden teeth" feeling
    • Teeth mobility
    • Fever
    • Malaise

Differential Diagnosis

Dentoalveolar Injuries

Odontogenic Infections

Other

Diagnosis

  • Usually clinical

Treatment

  • Organisms involved are polymycrobial but often include Fusobacterium necrophorum, Treponema spp, Selenomonas, and Prevotella
  • Chlorhexidine 0.01% oral rinse BID
  • Hydrogen peroxide swishing (cheap home remedy)
  • Oropharyngeal coverage:[3]
    • Penicillin V 500 mg PO q6 hours AND Metronidazole 500mg PO q8 hours x 10 days or
    • Amoxicillin 500 mg PO TID for 10d plus metronidazole 250 mg PO TID for 10d or
    • Amoxicillin-clavulanate 500 mg/125 mg PO TID or 875 mg/125 mg PO BID for 10d or
    • Clindamycin 150-300 mg PO TID for 10d or
    • Doxycycline 100 mg PO BID for 10d

HIV+

  • In addition to antibiotic regimen consider an oral anti-fungal or nystatin
    • Fluconazole 200mg PO daily for 14 days

Consultation

ENT or OMFS consult for dental debridement may be required in severe infections

See Also

References

  1. J Periodontol. 1986 Mar;57(3):141-50. Acute necrotizing ulcerative gingivitis. A review of diagnosis, etiology and treatment. Johnson BD, Engel D.
  2. J Periodontol. 1986 Mar;57(3):141-50. Acute necrotizing ulcerative gingivitis. A review of diagnosis, etiology and treatment. Johnson BD, Engel D.
  3. Stephen J. et al Acute Necrotizing Ulcerative Gingivitis Empiric Therapy. http://emedicine.medscape.com/article/2028117-overview. Accessed April 2015
  • ER Atlas