Difference between revisions of "Albendazole"

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==Adult Dosing==
 
==Adult Dosing==
 +
*Microsporidiosis: 400 mg po bid
 +
*neurocysticerosis: < 60 kg: 15 mg/kg/day PO BID x 8-30 days, max 800 mg/day. >60 kg: 400 mg PO BID x 8-30 days
  
 
==Pediatric Dosing==
 
==Pediatric Dosing==
 +
*neurocysticerosis: < 60 kg: 15 mg/kg/day PO BID x 8-30 days, max 800 mg/day. >60 kg: 400 mg PO BID x 8-30 days
  
 
==Special Populations==
 
==Special Populations==
*[[Drug Ratings in Pregnancy|Pregnancy Rating]]:
+
*[[Drug Ratings in Pregnancy|Pregnancy Rating]]:C
*Lactation:
+
*Lactation: unknown
 
*Renal Dosing
 
*Renal Dosing
**Adult
+
**Adult: not defined
**Pediatric
+
**Pediatric: not defined
 
*Hepatic Dosing
 
*Hepatic Dosing
**Adult
+
**Adult: not defined
**Pediatric
+
**Pediatric: not defined
  
 
==Contraindications==
 
==Contraindications==
Line 23: Line 26:
 
==Adverse Reactions==
 
==Adverse Reactions==
 
===Serious===
 
===Serious===
 
+
*leukopenia
 +
*neutropenia
 +
*pancytopenia
 +
*acute renal failure
 +
*hepatitis
 +
*SJS
 
===Common===
 
===Common===
 
+
*abnormal LFT's
 +
*abdominal pain
 +
*nausea/vomiting
 +
*headache
 +
*dizziness
 +
*alopecia
 +
*fever
 
==Pharmacology==
 
==Pharmacology==
*Half-life:  
+
*Half-life: 8-12 hour
*Metabolism:  
+
*Metabolism: liver
*Excretion:  
+
*Excretion: bile
*Mechanism of Action:
+
*Mechanism of Action: inhibits tublin polymerization
  
 
==See Also==
 
==See Also==

Revision as of 10:58, 15 May 2015

General

  • Type: antiparasitic
  • Dosage Forms: 200 mg
  • Common Trade Names:Albenza

Adult Dosing

  • Microsporidiosis: 400 mg po bid
  • neurocysticerosis: < 60 kg: 15 mg/kg/day PO BID x 8-30 days, max 800 mg/day. >60 kg: 400 mg PO BID x 8-30 days

Pediatric Dosing

  • neurocysticerosis: < 60 kg: 15 mg/kg/day PO BID x 8-30 days, max 800 mg/day. >60 kg: 400 mg PO BID x 8-30 days

Special Populations

  • Pregnancy Rating:C
  • Lactation: unknown
  • Renal Dosing
    • Adult: not defined
    • Pediatric: not defined
  • Hepatic Dosing
    • Adult: not defined
    • Pediatric: not defined

Contraindications

  • Allergy to class/drug

Adverse Reactions

Serious

  • leukopenia
  • neutropenia
  • pancytopenia
  • acute renal failure
  • hepatitis
  • SJS

Common

  • abnormal LFT's
  • abdominal pain
  • nausea/vomiting
  • headache
  • dizziness
  • alopecia
  • fever

Pharmacology

  • Half-life: 8-12 hour
  • Metabolism: liver
  • Excretion: bile
  • Mechanism of Action: inhibits tublin polymerization

See Also

Sources