Difference between revisions of "Alpha-2 agonists"

(Created page with "==Background== Central alpha agonists lower blood pressure by stimulating alpha-receptors in the brain which open peripheral arteries easing blood flow. These Alpha-2 adrene...")
 
(Medications)
 
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==Background==
 
==Background==
Central alpha agonists lower blood pressure by stimulating alpha-receptors in the brain which open peripheral arteries easing blood flow. These [[Alpha-2 adrenergic receptor|alpha 2 receptors]] are known as [[autoreceptors]] which provide a negative feedback in neurotransmission (in this case, the vasoconstriction effects of adrenaline).
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*Central α agonists lower blood pressure by stimulating α-receptors in the brain which causes peripheral vasodilation
Central alpha agonists, such as clonidine, are usually prescribed when all other anti-hypertensive medications have failed. For treating hypertension, these drugs are usually administered in combination with a diuretic.
 
  
 
==Medications==
 
==Medications==
* [[clonidine]]
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*[[clonidine]]
* [[guanabenz]]
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*[[dexmedetomidine]]
* [[guanfacine]]
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*[[guanabenz]]
* [[methyldopa]]
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*[[guanfacine]]
* [[moxonidine]]
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*[[methyldopa]]
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*[[moxonidine]]
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*[[Xylazine toxicity|Xylazine]] (veterinary med, drug of abuse)
  
 
==Adverse effects==
 
==Adverse effects==
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==See Also==
 
==See Also==
 
*[[Antihypertensives]]
 
*[[Antihypertensives]]
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[[Category:Pharmacology]]

Latest revision as of 16:54, 29 November 2020

Background

  • Central α agonists lower blood pressure by stimulating α-receptors in the brain which causes peripheral vasodilation

Medications

Adverse effects

  • sedation
  • drying of the nasal mucosa
  • rebound hypertension

See Also