Amphetamines: Difference between revisions

No edit summary
No edit summary
Line 1: Line 1:
==Background==
==Background==
*Unlike cocaine, duration of action may be 12hr or longer
*Unlike cocaine, duration of action may be 12hr or longer
- Time- oral- 30min, inhaled instant
- Time- oral- 30min, inhaled instant



Revision as of 03:47, 5 January 2012

Background

  • Unlike cocaine, duration of action may be 12hr or longer

- Time- oral- 30min, inhaled instant

- hepatic and renal excretion- lasts 6- 24 hrs

- if tolerance developes- physical exam may yield normal findings

- desipramine and amantadine can give false positive for urine amphet test

- hallucinogenic amphet deriv may not show up on tox screen AKA Entactogens- enabling user to touch within

Methamphetamine

  • More combative
  • Delusions of parasites, formication, self-mutilate
  • more dysphoric

MDMA Ecstacy

  • Increases serotonin, dopamine
  • Lasts 3 - 5hrs
  • Hyponatremia

Diagnosis

Alpha

  • pupils dilate
  • sweat
  • decrease gi peristalsis
  • constrict blood vessels

Beta

  • inc HR and contractility
  • dilate bronchi
  • dilate muscle beds

Mixed

  • delusions, paranoia, aggression, poor judgement, hallucinate, confusion

Treatment

  • Benzos

See Also

Toxidromes

Source

MISTRY 6/06