Difference between revisions of "Behçet's disease"

(Differential Diagnosis)
(Management)
 
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==Differential Diagnosis==
 
==Differential Diagnosis==
 
*[[HSV]]
 
*[[HSV]]
*[[lichen planus]]
+
*[[Lichen planus]]
*[[pemphigus vulgaris]]
+
*[[Pemphigus vulgaris]]
*[[pemphigoid]]
+
*[[Bullous pemphigoid]]
 
*IVD
 
*IVD
 
*[[SJS]]
 
*[[SJS]]
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*Severe mucocutaneous disease: [[Prednisone]] 1mg/kg, low-dose thalidomide, or methotrexate
 
*Severe mucocutaneous disease: [[Prednisone]] 1mg/kg, low-dose thalidomide, or methotrexate
 
*Systemic disease: Steroid +/- [[cyclophosphamide]] or [[azathioprine]]
 
*Systemic disease: Steroid +/- [[cyclophosphamide]] or [[azathioprine]]
*Ocular: Prednisone + azathioprine and rapid ophthalmologist referral
+
*Ocular: [[Prednisone]] + [[azathioprine]] and rapid ophthalmologist referral
 
*Cerebral [[venous sinus thrombosis]]- [[heparin]]
 
*Cerebral [[venous sinus thrombosis]]- [[heparin]]
  

Latest revision as of 23:32, 17 October 2019

Background

Behcet's.png
  • Chronic small-vessel vasculitis
  • Mucocutaneous, ocular, cardiovascular, renal, GI, pulmonary, urologic, musculoskeletal, CNS involvement
  • Aphthous oral ulcers + ≥ 2 of following: Genital aphthae, cutaneous lesions, and neurological, oral or rheumatologic manifestations

Clinical Features

Differential Diagnosis

Evaluation

  • Clinical diagnosis
  • ESR/CRP elevated

Classification

  • International Study Group Criteria
  • Recurrent oral aphthae (at least 3 times in 1 year) + 2 of the following in absence of other systemic diseases:
    • Recurrent genital aphthae
    • Eye lesions
    • Skin lesions
    • A positive pathery test

Management

References

  • Rosen's Emergency Medicine 8th edition. 2013. Chapter: Erythematosus and the Vasculitides. p1540.
  • Smith EL, et al. Clinical manifestations and diagnosis of Behcet's disease. In: Post T, ed. UpToDate. Waltham, Mass.: UpToDate; 2014. www.uptodate.com. Accessed December 22, 2014.
  • Alnaimat FA, et al. (2014, Dec 16). Behcet Disease. eMedicine. Retrieved 12/22/2014 from http://emedicine.medscape.com/article/329099-overview
Authors: