Chondrosarcoma: Difference between revisions

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==Background==
==Background<ref>Niederhuber, John E., et al. “Sarcomas.” Abeloff's Clinical Oncology E-Book. Elsevier Health Sciences, 2019, pp. 1604 – 1654.e8.</ref>==
*Third most common primary bone malignancy after [[multiple myeloma]] and [[osteosarcoma]]
*Third most common primary bone malignancy after [[multiple myeloma]] and [[osteosarcoma]]
*Around ninety percent of chondrosarcomas are of low metastatic potential
*Around ninety percent of chondrosarcomas are of low metastatic potential
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==Differential Diagnosis==
==Differential Diagnosis==
 
{{Bone tumors and their mimics DDX}}


==Evaluation==
==Evaluation==
 
[[File:Mrichondrosarcoma.jpg|thumb|MRI of a left-pelvis with chondrosarcoma]]
*Plain radiographs reveal punctate calcifications and cortical bone destruction
*CT or MRI to assess extent of bone involvement
*Bone biopsy for definitive diagnosis


==Management==
==Management==
 
*Surgery is the definitive treatment
*Radiation and chemotherapy are ineffective as tumor is very slow growing


==Disposition==
==Disposition==
 
*Home with outpatient follow up


==References==
==References==
<references/>
<references/>
[[Category:Orthopedics]]
[[Category:Heme/Onc]]

Latest revision as of 01:12, 22 October 2020

Background[1]

Pathophysiology

  • Overproduction of chondroid matrix in the medullary cavity

Clinical Features

  • Lesions commonly in the pelvis and central skeleton
  • Occurs in patients over 40 years-old with a male predominance
  • Often will present with local swelling and pain or a pathologic fracture
  • Very slow growing tumors

Differential Diagnosis

Bone tumors and their mimics

Malignant

Benign

Other

Evaluation

MRI of a left-pelvis with chondrosarcoma
  • Plain radiographs reveal punctate calcifications and cortical bone destruction
  • CT or MRI to assess extent of bone involvement
  • Bone biopsy for definitive diagnosis

Management

  • Surgery is the definitive treatment
  • Radiation and chemotherapy are ineffective as tumor is very slow growing

Disposition

  • Home with outpatient follow up

References

  1. Niederhuber, John E., et al. “Sarcomas.” Abeloff's Clinical Oncology E-Book. Elsevier Health Sciences, 2019, pp. 1604 – 1654.e8.