Chondrosarcoma

Revision as of 01:12, 22 October 2020 by ClaireLewis (talk | contribs)
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)

Background[1]

Pathophysiology

  • Overproduction of chondroid matrix in the medullary cavity

Clinical Features

  • Lesions commonly in the pelvis and central skeleton
  • Occurs in patients over 40 years-old with a male predominance
  • Often will present with local swelling and pain or a pathologic fracture
  • Very slow growing tumors

Differential Diagnosis

Bone tumors and their mimics

Malignant

Benign

Other

Evaluation

MRI of a left-pelvis with chondrosarcoma
  • Plain radiographs reveal punctate calcifications and cortical bone destruction
  • CT or MRI to assess extent of bone involvement
  • Bone biopsy for definitive diagnosis

Management

  • Surgery is the definitive treatment
  • Radiation and chemotherapy are ineffective as tumor is very slow growing

Disposition

  • Home with outpatient follow up

References

  1. Niederhuber, John E., et al. “Sarcomas.” Abeloff's Clinical Oncology E-Book. Elsevier Health Sciences, 2019, pp. 1604 – 1654.e8.