Ciprofloxacin: Difference between revisions
Line 32: | Line 32: | ||
*'''Post-Exposure Prophylaxis''' | *'''Post-Exposure Prophylaxis''' | ||
**500mg PO q12h x 60 days (or exposure excluded) | **500mg PO q12h x 60 days (or exposure excluded) | ||
===[[Typhoid Fever]]=== | |||
*500mg PO q12h x 2 weeks | |||
===[[Chancorid]]=== | |||
*500mg PO q12h x 3 days | |||
===[[Salmonella]]=== | |||
*''Acute''' | |||
**500-750mg PO q12h x 3-7 days | |||
***Extend treatment x 1 week if immunocompromised | |||
*'''Chronic Carrier''' | |||
**750mg PO q12h x 1 month | |||
==Pediatric Dosing== | ==Pediatric Dosing== |
Revision as of 03:25, 19 March 2014
General
- Type: Fluoroquinolones
- Dosage Forms: IV; PO (Standard: 100, 250, 500; ER 500, 1000)
- Common Trade Names: Cipro
Adult Dosing
General
- PO
- 250-750mg PO q12h
- First Dose: 250-750mg PO x1
- IV
- 200-400mg IV q12
- First Dose: 400mg IV x 1
- Alt: 400mg IV q8h
UTI
- Uncomplicated
- 500mg ER PO q24h x 3 days
- Alt: 250mg PO q12h x 3 days
- Complicated
- IV: 400mg IV q12h x 7-14 days
- PO: 1000mg ER PO q24h x 7-14 days
- Alt: 500mg PO q12h x 7-14 days
Anthrax
- Inhalational, Gi, oropharyngeal
- 400mg IV q12h OR 500mg PO q12 x 60 days
- First dose: 400mg IV + 1-2 additional antibiotics
- Cutaneous
- 400mg IV q12h OR 500mg PO q12 x 7-10 days
- Info: Give x 60 days if bioterrorism suspected
- 400mg IV q12h OR 500mg PO q12 x 7-10 days
- Post-Exposure Prophylaxis
- 500mg PO q12h x 60 days (or exposure excluded)
Typhoid Fever
- 500mg PO q12h x 2 weeks
Chancorid
- 500mg PO q12h x 3 days
Salmonella
- Acute'
- 500-750mg PO q12h x 3-7 days
- Extend treatment x 1 week if immunocompromised
- 500-750mg PO q12h x 3-7 days
- Chronic Carrier
- 750mg PO q12h x 1 month
Pediatric Dosing
Special Populations
- Pregnancy: C (but indicated for anthrax)
- Lactation: Probably safe
- Renal Dosing
- Adult
- Pediatric
- Hepatic Dosing
- Adult
- Pediatric
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
Common
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
- Mechanism of Action: