Clonorchis sinensis: Difference between revisions
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==Clinical Features== | ==Clinical Features== | ||
*Usually asymptomatic | *Usually asymptomatic | ||
*[[Abdominal pain]], [[diarrhea]], [[constipation | *[[Abdominal pain]], [[diarrhea]], [[constipation]] | ||
*Long-term infection can result in severe illness | *Long-term infection can result in severe illness | ||
**[[Hepatomegaly]] | **[[Hepatomegaly]] | ||
**Malnutrition | **Malnutrition | ||
**Increased risk of cholangiocarcinoma and hepatic cancers due to inflammation | **Increased risk of cholangiocarcinoma and hepatic cancers due to inflammation<ref>Krasinskas AM. Cholangiocarcinoma. Surg Pathol Clin. 2018;11(2):403–429.</ref> | ||
==Differential Diagnosis== | ==Differential Diagnosis== | ||
Latest revision as of 21:11, 22 December 2020
Background
- AKA oriental liver fluke, found in Asia
- Transmitted by ingestion of infected, undercooked fish, crabs, or crayfish
- Infect liver, gallbladder, bile ducts
- Fluke can live in a person for 25-30 years if left untreated
Clinical Features
- Usually asymptomatic
- Abdominal pain, diarrhea, constipation
- Long-term infection can result in severe illness
- Hepatomegaly
- Malnutrition
- Increased risk of cholangiocarcinoma and hepatic cancers due to inflammation[1]
Differential Diagnosis
Helminth infections
Cestodes (Tapeworms)
- Taenia saginata
- Taenia solium (Cysticercosis)
- Diphyllobothrium latum
- Hymenolepis nana
- Echinococcus granulosus
Trematodes (Flukes)
- Fasciola hepatica
- Fasciolopsis buski
- Opistorchis viverrini
- Schistosoma spp
- Chlonorchis sinensis
- Paragonimus spp.
Nematodes (Roundworms)
- Ascaris lumbricoides
- Enterobius vermicularis (Pinworm)
- Filarial worms
- Hookworm
- Necator americanus
- Ancylostoma duodenale
- Cutaneous larva migrans (Ancylostoma braziliense)
- Dracunculiasis
- Strongyloides stercoralis
- Trichuris trichiura (Whipworm)
- Anisakis
- Toxocara spp.
- Trichinosis
Evaluation
- Definitive diagnosis made by identification of eggs and flukes in stool
Management
- Praziquantel 25mg/kg PO q8h x 2 days
Disposition
- Discharge, likely
See Also
External Links
References
- ↑ Krasinskas AM. Cholangiocarcinoma. Surg Pathol Clin. 2018;11(2):403–429.