Coagulopathy (main): Difference between revisions

Revision as of 18:46, 20 July 2017

Primary hemostasis: damage to endothelial basement membrane and formation of platelet plug
Secondary hemostasis: coagulation cascade

Coagulation cascade

Authors:

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-==DDX==
+==Background==
-*[[Vitamin K Deficiency]]
+*Primary hemostasis: damage to endothelial basement membrane and formation of platelet plug
-*[[Warfarin (Coumadin)]]
+*Secondary hemostasis: coagulation cascade
-*[[Heparin]]
+[[File:Coagulation cascade.png|thumbnail|Coagulation cascade]]
-*[[Lovenox]]
-*[[DIC]]
-*[[Hemophilia]]
-*[[Factor VIII Inhibitor]]
-*[[Lupus Anticoagulan]]t]]
-*[[Liver Disease Induced Coagulopathy]]
-*[[Renal Disease Induced Coagulopathy]]
+==Clinical Features==
+*Spontaneous bleeding
+*Bleeding out of proportion
+*Swollen joints
+*[[Epistaxis]]
+*Bleeding gums
+*Menometrorrhagia
+*Easy bruising/petechiae
+*Hematuria
+==Differential Diagnosis==
+{{Increased bleeding DDX}}
+===Increased Clotting===
+*[[Disseminated Intravascular Coagulation (DIC)]]
 ==Managment==
-*[[Procedures in Patients with Coagulopathies]]
 *[[Bleeding Treatments]]
-*[[Warfarin (Coumadin) Reversal]]
+*[[Procedures in patients with coagulopathies]]
+*[[Anticoagulant reversal]] (known medications)
+**[[Warfarin (Coumadin) Reversal]]
+**[[Dabigatran (Pradaxa) Reversal]]
+**[[Rivaroxaban reversal]]
+**[[Unfractionated heparin reversal]]
+*[[Anti-platelet agent reversal]]
 ==See Also==
+*[[Transfusions]]
+*[[Idarucizumab]]
-==Source==
+==References==
-*Tintinalli
+<references/>
-*UpToDate
 [[Category:Heme/Onc]]