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  • Type:
  • Dosage Forms:
  • Routes of Administration:
  • Common Trade Names:

Adult Dosing

Iron toxicity

  • 1000mg IV; start at 5mg/kg/hr, increase up to 15mg/kg/hr as tolerated for up to 24hrs
  • Subsequent doses are 500mg increments guided by clinical status of patient / urine color
  • Recommended amount during first 24hr is 360mg/kg not to exceed 6g.

Pediatric Dosing

Special Populations


  • Systemic toxicity and iron level > 350 mcg/dL
  • Metabolic acidosis
  • Progressive symptoms
  • Serum iron level >500 mcg/dL


  • Allergy to class/drug
  • Renal failure patients not on hemodialysis

Adverse Reactions


  • Half-life:
  • Metabolism:
  • Excretion:
  • Mechanism of Action:


  • Chelates iron and creates a water-soluble compound ferrioxamine that is renally excreted and can be dialyzed.[2]

See Also


  1. Mazzoleni G. et al. Yersinia enterocolitica infection with ileal perforation associated with iron overload and deferoxamine therapy. Dig Dis Sci 1991; 36:1154-1160.
  2. Cite error: Invalid <ref> tag; no text was provided for refs named ironoverview