Dextromethorphan

Administration

• Type: Anti-tussive
• Dosage Forms:
• Routes of Administration:
• Common Trade Names: Active ingredient in many combination OTC cough/cold medications

Adult Dosing

• 30mg PO q6-8h

Pediatric Dosing

• cough/cold products should NOT be used in children younger than 4 years

Special Populations

• Pregnancy Rating: A
• Lactation risk: infant risk minimal

Renal Dosing

• Adult:
• Pediatric:

Hepatic Dosing

• Adult:
• Pediatric:

Contraindications

• Allergy to class/drug
• MAOI use concurrently or within past 14d

Adverse Reactions

Serious

• Serotonin syndrome (if used with other serotonergic agents)
• Recreational abuse

Common

• Dizziness
• Fatigue/somnolence

Pharmacology

• Half-life:
• Metabolism: Liver
• Excretion: Renal

References

Micromedex