Difference between revisions of "Dobutamine"

(General)
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<references/>
 
<references/>
 
[[Category:Drugs]]
 
[[Category:Drugs]]
 +
 +
===Indication===
 +
*Cardiogenic shock
 +
*Low-output heart failure
 +
*Tricyclic overdose
 +
===Primary Receptor===
 +
* β1
 +
* β2
 +
===Relative Effects===
 +
*↑↑↑SV
 +
*↑↑HR
 +
*↓SVR (transient, from β2 agonism)
 +
===Dosing===
 +
*2-20mcg/kg/min
 +
**10mcg works for most
 +
*May use in peripheral IV
 +
===Rate of Titration===
 +
*Q2-5 min
 +
===Adverse Effects===
 +
*Tachyarrhythmias
 +
*Myocardial ischemia
 +
*Hypotension as β2 effect may result in vasodilation
 +
**Caution if SBP <90

Revision as of 14:10, 20 December 2014

General

Adult Dosing

Pediatric Dosing

Special Populations

  • Pregnancy Rating:
  • Lactation:
  • Renal Dosing
    • Adult
    • Pediatric
  • Hepatic Dosing
    • Adult
    • Pediatric

Contraindications

  • Allergy to class/drug

Adverse Reactions

Serious

Common

Pharmacology

  • Half-life:
  • Metabolism:
  • Excretion:
  • Mechanism of Action:

See Also

Sources


Indication

  • Cardiogenic shock
  • Low-output heart failure
  • Tricyclic overdose

Primary Receptor

  • β1
  • β2

Relative Effects

  • ↑↑↑SV
  • ↑↑HR
  • ↓SVR (transient, from β2 agonism)

Dosing

  • 2-20mcg/kg/min
    • 10mcg works for most
  • May use in peripheral IV

Rate of Titration

  • Q2-5 min

Adverse Effects

  • Tachyarrhythmias
  • Myocardial ischemia
  • Hypotension as β2 effect may result in vasodilation
    • Caution if SBP <90