Difference between revisions of "Dobutamine"

Line 5: Line 5:
  
 
==Adult Dosing==
 
==Adult Dosing==
 +
===Dosing===
 +
*2-20mcg/kg/min
 +
**10mcg works for most
 +
*May use in peripheral IV
 +
===Rate of Titration===
 +
*Q2-5 min
  
 
==Pediatric Dosing==
 
==Pediatric Dosing==
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==Adverse Reactions==
 
==Adverse Reactions==
 +
*Tachyarrhythmias
 +
*Myocardial ischemia
 +
*Hypotension as β2 effect may result in vasodilation
 +
**Caution if SBP <90
 +
 
===Serious===
 
===Serious===
  
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*Excretion:  
 
*Excretion:  
 
*Mechanism of Action:
 
*Mechanism of Action:
 +
===Primary Receptor===
 +
* β1
 +
* β2
 +
===Relative Effects===
 +
*↑↑↑SV
 +
*↑↑HR
 +
*↓SVR (transient, from β2 agonism)
 +
 +
==Notes==
 +
===Indications===
 +
*Cardiogenic shock
 +
*Low-output heart failure
 +
*Tricyclic overdose
  
 
==See Also==
 
==See Also==
Line 38: Line 62:
 
<references/>
 
<references/>
 
[[Category:Drugs]]
 
[[Category:Drugs]]
 
===Indication===
 
*Cardiogenic shock
 
*Low-output heart failure
 
*Tricyclic overdose
 
===Primary Receptor===
 
* β1
 
* β2
 
===Relative Effects===
 
*↑↑↑SV
 
*↑↑HR
 
*↓SVR (transient, from β2 agonism)
 
===Dosing===
 
*2-20mcg/kg/min
 
**10mcg works for most
 
*May use in peripheral IV
 
===Rate of Titration===
 
*Q2-5 min
 
===Adverse Effects===
 
*Tachyarrhythmias
 
*Myocardial ischemia
 
*Hypotension as β2 effect may result in vasodilation
 
**Caution if SBP <90
 

Revision as of 14:23, 20 December 2014

General

Adult Dosing

Dosing

  • 2-20mcg/kg/min
    • 10mcg works for most
  • May use in peripheral IV

Rate of Titration

  • Q2-5 min

Pediatric Dosing

Special Populations

  • Pregnancy Rating:
  • Lactation:
  • Renal Dosing
    • Adult
    • Pediatric
  • Hepatic Dosing
    • Adult
    • Pediatric

Contraindications

  • Allergy to class/drug

Adverse Reactions

  • Tachyarrhythmias
  • Myocardial ischemia
  • Hypotension as β2 effect may result in vasodilation
    • Caution if SBP <90

Serious

Common

Pharmacology

  • Half-life:
  • Metabolism:
  • Excretion:
  • Mechanism of Action:

Primary Receptor

  • β1
  • β2

Relative Effects

  • ↑↑↑SV
  • ↑↑HR
  • ↓SVR (transient, from β2 agonism)

Notes

Indications

  • Cardiogenic shock
  • Low-output heart failure
  • Tricyclic overdose

See Also

Sources