Empyema: Difference between revisions

(Text replacement - "Category:Pulm" to "Category:Pulmonary")
(Text replacement - "*CXR" to "*CXR")
(5 intermediate revisions by 2 users not shown)
Line 3: Line 3:
*Stages
*Stages
*#Exudative - Free-flowing pleural effusion amenable to chest tube drainage; may only last <48hr
*#Exudative - Free-flowing pleural effusion amenable to chest tube drainage; may only last <48hr
*#Fibrinopurulent - Loculations develop making resolution w/ single chest tube drainage unlikely
*#Fibrinopurulent - Loculations develop making resolution with single chest tube drainage unlikely
*#Organizational - Takes several weeks to develop; "pleural peel" restricts lung expansion
*#Organizational - Takes several weeks to develop; "pleural peel" restricts lung expansion


Line 29: Line 29:
*[[Tuberculosis]]
*[[Tuberculosis]]
*[[Pleural Effusion]]
*[[Pleural Effusion]]
*[[Wegener's granulomatosis]]
*[[Granulomatosis with polyangiitis]] (wegener's)
*[[Pulmonary embolism]]
*[[Pulmonary embolism]]


==Diagnosis==
==Evaluation==
===Work Up===
===Work Up===
*CBC
*CBC
*CXR
*[[CXR]]
*[[Thoracentesis]]
*[[Thoracentesis]]
*Sputum Culture -- Acid Fast Bacilli (If TB suspected)
*Sputum Culture -- Acid Fast Bacilli (If TB suspected)
Line 50: Line 50:
**LDH >1000 IU/mL
**LDH >1000 IU/mL


==Treatment==
==Management==
*Treat underlying disease
*Treat underlying disease
*O2 if [[Hypoxemia]]
*O2 if [[Hypoxemia]]
Line 57: Line 57:
*[[Antibiotics]]
*[[Antibiotics]]
**[[Piperacillin-tazobactam]] 3.375-4.5gm q6hr IV or [[imipenem]] 0.5-1gm q6hr
**[[Piperacillin-tazobactam]] 3.375-4.5gm q6hr IV or [[imipenem]] 0.5-1gm q6hr
**Consider adding [[vancomycin]] if pt at risk for [[MRSA]]
**Consider adding [[vancomycin]] if patient at risk for [[MRSA]]


{{Chest tube size table}}
{{Chest tube size table}}

Revision as of 08:03, 9 September 2016

Background

  • Pleural space infections with + Gram stain/culture OR parapneumonic effusions without pleural fluid sampling
  • Stages
    1. Exudative - Free-flowing pleural effusion amenable to chest tube drainage; may only last <48hr
    2. Fibrinopurulent - Loculations develop making resolution with single chest tube drainage unlikely
    3. Organizational - Takes several weeks to develop; "pleural peel" restricts lung expansion

Causes

Clinical Features

Differential Diagnosis

Evaluation

Work Up

Evaluation

  • Aspiration of grossly purulent pleural fluid on thoracentesis and at least 1 of the following:[2]
    • + Gram stain or culture
    • WBC count > 50,000 cells/µL (or polymorphonuclear leukocyte count of 1,000 IU/dL)
    • Pleural fluid glucose <60
    • pH <7.2
    • LDH >1000 IU/mL

Management

Adult Chest Tube Sizes

Chest Tube Size Type of Patient Underlying Causes
Small (8-14 Fr)
  • Alveolar-pleural fistulae (small air leak)
  • Iatrogenic air
Medium (20-28 Fr)
  • Trauma/bleeding (hemothorax/hemopneumothorax)
  • Bronchial-pleural fistulae (large air leak)
  • Malignant fluid
Large (36-40 Fr)
  • Thick pus

See Also

References

  1. Barmparas G, DuBose J, Teixeira PG, Recinos G, Inaba K, Plurad D. Risk factors for empyema after diaphragmatic injury: results of a National Trauma Databank analysis. J Trauma. Jun 2009;66(6):1672-6
  2. http://emedicine.medscape.com/article/807499-overview
  3. Inaba Et. al J Trauma Acute Care Surg. 2012 Feb;72(2):422-7.
  4. Advanced Trauma Life Support® Update 2019: Management and Applications for Adults and Special Populations.