Difference between revisions of "Enoxaparin"

(Adverse Reactions)
(Adverse Reactions)
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==Adverse Reactions==
 
==Adverse Reactions==
 
*Bleeding
 
*Bleeding
**Treatment = Protamine
 
***Does not completely reverse LMWHs
 
***Carries significant anaphylaxis risk (0.2%); only use for major bleeding
 
***Protamine 1mg IV for every 1mg of enoxaparin given in previous 8h
 
****If 8–12h since last enoxaparin dose give 0.5mg IV for every 1mg of enoxaparin given
 
 
*Pruritus
 
*Pruritus
 
*Local skin reaction
 
*Local skin reaction

Revision as of 13:35, 3 April 2016

General

Adult Dosing

Pediatric Dosing

Special Populations

  • Pregnancy Rating:
  • Lactation:
  • Renal Dosing
    • Renal impairment (Cr clearance <30)
      • Use 50% of usual dose or use UFH instead
    • Adult
    • Pediatric
  • Hepatic Dosing
    • Adult
    • Pediatric
  • Obesity
    • Weight-based dosing safe up to 190kg (no data available thereafter)

Indications

Contraindications

  • Allergy to class/drug

Adverse Reactions

  • Bleeding
  • Pruritus
  • Local skin reaction

Pharmacology

  • Half-life:
  • Metabolism:
  • Excretion:
  • Mechanism of Action:

See Also

Sources