Ethanol toxicity: Difference between revisions

m (Rossdonaldson1 moved page Ethanol Toxicity to Ethanol toxicity)
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##Lactic acidosis
##Lactic acidosis
##Epigastric pain (pancreatitis)
##Epigastric pain (pancreatitis)
==Differential Diagnosis==
{{Sedatve/hypnotic toxicity types}}


==Diagnosis==
==Diagnosis==
#Blood sugar
#Blood sugar
#BAL
#BAL
##Appropriate if AMS is due to unknown cause
#*Appropriate if AMS is due to unknown cause
##Not necessarily required in mild-mod intoxication or if no other abnormality suspected
#*Not necessarily required in mild-mod intoxication or if no other abnormality suspected
#Elevated osmolar gap
#Elevated osmolar gap



Revision as of 16:29, 12 March 2015

Background

  • AMS that doesn't improve after few hrs is due to alternative cause until proven otherwise
  • Blood Alcohol Level
    • Correlates poorly with degree of intoxication
    • Rate of ETOH elimination is 15-30mg/dL/hr (depending on degree of chronic alcoholism)

Clinical Features

  1. Classic Features
    1. Slurred speech
    2. Nystagmus
    3. Ataxia
    4. N/V
    5. Respiratory depression
    6. Coma
  2. Other Features (if malnourished)
    1. Hypoglycemia
    2. Ketoacidosis
    3. Lactic acidosis
    4. Epigastric pain (pancreatitis)

Differential Diagnosis

Sedative/hypnotic toxicity

Diagnosis

  1. Blood sugar
  2. BAL
    • Appropriate if AMS is due to unknown cause
    • Not necessarily required in mild-mod intoxication or if no other abnormality suspected
  3. Elevated osmolar gap

Treatment

  1. GI decontamination
    1. Activated charcoal ineffective (ETOH is too rapidly absorbed)
  2. Hypoglycemia
    1. Give glucose immediately (do not have to wait to give thiamine first)
  3. "Banana Bag"
    1. IV form is not justified
    2. Likelihood of vitamin deficiency (except for thiamine) is low
    3. IVF does not hasten ETOH elimination

Disposition

  • Most pts require observation only
  • Can be discharged once patient at baseline mental status, able to tolerate PO, and road test successful

See Also

Source

  • Tintinalli