Healthcare occupational exposure to blood or other body fluids: Difference between revisions
(Created page with "BLOOD BODY FLUID EXP HIV - risk is 0.3% xmission rate for needle stick- less for mucous mem - risk increases with quantity of blood, needle in vein or art, or deep inj, or ...") |
No edit summary |
||
Line 1: | Line 1: | ||
BLOOD BODY FLUID EXP | BLOOD BODY FLUID EXP | ||
HIV | HIV | ||
Line 109: | Line 107: | ||
6/06 MISTRY | 6/06 MISTRY | ||
HEP B | HEP B | ||
Line 119: | Line 116: | ||
--> HBIG + vaccine | --> HBIG + vaccine | ||
==See Also== | ==See Also== | ||
See ID: HIV (Occupational) | See ID: HIV (Occupational) | ||
[[Category:ID]] | [[Category:ID]] |
Revision as of 05:00, 28 March 2011
BLOOD BODY FLUID EXP
HIV
- risk is 0.3% xmission rate for needle stick- less for mucous mem
- risk increases with quantity of blood, needle in vein or art, or deep inj, or source pt terminal with high viral titre
- may get PEP failure if resist strain of hiv, high titre, large volume, delayed initiation of PEP or too short course, weak host immune syst, syncytia forming strains of hiv
- rec use rapid hiv test to test source pt to decrease need for unnessasary hiv prophylaxsis. give at least one dose until source pt confirmed as neg
- 3 drug therapy only is skin puntured and source pt hiv+
- HIV PEP consists of:
4 wks of ZDV and 3TC or
3TC and d4t or
d4T and ddI
- side effects- NVD, pancreatittis, dm, kidney stone, skin reactions
- may add third drug for expanded risk of xmission- source pt resistant if dz progressing, viral load still high, cd4 count dropping despite tx
- if source pt resistant, choose drug accordingly
- if source pt hiv neg, and no sxs of aids or acute retroviral syndrome, chance of source pt being in "window" period small and no further testing of stuck pt needed
- no testing of sharps or needles
- if don't know about source pt, start tx for 4 wks. if source pt later known to be neg, can stop
Feces, snot, spit, sweat, tears, vomit, urine not infectious unless contain blood.
Human bite- tx both pt and source. rare route of xmission
Hep B
- risk of infc 2- 30% after needle stick
- can survive on dried blood for 1 wk
- found in all fluids but highest conc in blood and therefore highest risk with blood
- hep b surface antibodies confers life long immunity
- don't need to test pt or source if pt certain fully/ successfully immunized- antibodies > 10 IU at some time
- if pt not successfully immunized, give hep b immune globulin
- failed 3 shots/ 1 series- give hep booster and immune globulin x 2 doses over 1 mo
- failed 6 shots/ 2 series- give sequential immune globulin
Hep C
- no prophylaxsis
- no interferon, no antivirals, no globulin
- not xmitted efficiently through needle stick- 2% rate
- get basline hcv test and ALT
Post Exp Viral Hep Counseling
- can still breast feed
- no organ/ blood donation
- no worry about modifiying sex pattern or becoming preg
www.needlestick.mednet.ucla.edu
6/06 MISTRY
hep b core antibody if unvaccinated
hep b surface antibody if vaccinated
tx c
combivir 300/150 1 po bid
indinavir IDV 400mg 2 po tid
6/06 MISTRY
HEP B
Patient Source
Unvaccinated Pos
--> HBIG + vaccine
See Also
See ID: HIV (Occupational)