Isoproterenol

Revision as of 21:09, 5 August 2016 by Kxl328 (talk | contribs)

General

Adult Dosing

  • Loading dose: 0.02-0.06 mg IV, followed by infusion[1][2]
    • 2-20 mcg/min IV infusion
    • Titrate to HR and BP

Pediatric Dosing

  • No well controlled studies for appropriate dosing
  • AHA recommends initial infusion of 0.1 mcg/kg/min, with titrated range usually 0.1-1 mcg/kg/min[3]

Special Populations

Indications

  • Refractory torsades
  • Refractory symptomatic bradycardia

Contraindications

  • Allergy to class/drug

Adverse Reactions

  • Dramatic increase in O2 demand
  • V-tach (use lowest dose possible)

Pharmacology

  • Half-life:
  • Metabolism:
  • Excretion:
  • Mechanism of Action:

Kinetics

  • Onset of action = 1-5min
  • Duration of action = 1-2hr

Comments

See Also

References

  1. GlobalRPH. Isoproterenol Dilution. http://www.globalrph.com/isoproterenol_dilution.htm.
  2. AthenaHealth. Epocrates. Isoproterenol - Entire Monograph. https://online.epocrates.com/u/10a106/isoproterenol.
  3. GlobalRPH. Isoproterenol Dilution. http://www.globalrph.com/isoproterenol_dilution.htm.