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  • Defined as concurrent inflammation of both the cornea and conjunctiva.
  • Multiple etiologies:
    • Atopic keratoconjunctivitis: common in patients with atopy(ie: eczema, allergies, asthma, rhinitis)
    • Epidemic keratoconjunctivitis: highly contagious viral(Adenovirus) conjunctivitis, associated with watery discharge
    • Keratoconjunctivitis photoelectrica(subtype of UV Keratitis)
    • Keratoconjunctivitis sicca: associated with autoimmune disorders such as Sjogren's Syndrome, Sarcoidosis, Rheumatoid arthritis, and Schleroderma

Clinical Features

  • intense itching
  • excessive tearing
  • burning sensation
  • clear mucus discharge
  • conjunctival erythema/hyperemia
  • blurred vision
  • photophobia
  • foreign body sensation
  • Thickened, scaly, indurated eyelids are characteristic of Atopic Keratoconjunctivitis
  • Chronic inflammation may eventually lead to vision loss

Differential Diagnosis


  • Generally clinical


Based on likely etiology and severity:


  • Mild: basic eye care(resist itching, cold compress, artificial tears), antihistamines, mast cell stabilizers
  • Moderate/Severe: should be referred to Ophthalmologist


  • Atopic keratoconjunctivitis: chronic management should be determined by Ophthalmologist
  • Epidemic keratoconjunctivitis: usually self-resolving
  • Keratoconjunctivitis photoelectrica: eye rest and proper eye protection
  • Keratoconjunctivitis sicca: chronic management should be determined by Ophthalmologist


See Also

External Links