Difference between revisions of "Klebsiella"

m (Rossdonaldson1 moved page Klebsiella to Klebsiella pneumoniae)
 
(5 intermediate revisions by 2 users not shown)
Line 1: Line 1:
 
==Background==
 
==Background==
 +
The majority of Klebsiella infections are caused by K. pneumoniae, followed by K. oxytoca.
 +
==Characteristics==
 +
*[[Gram-negative]]
 +
*Lactose-fermenting
 +
**Grows pink on MacConkey agar
 +
*Urease positive
 +
 +
==Differential Diagnosis==
 +
{{Causes of pneumonia}}
  
 
==[[Antibiotic Sensitivities]]<ref>Sanford Guide to Antimicrobial Therapy 2014</ref>==
 
==[[Antibiotic Sensitivities]]<ref>Sanford Guide to Antimicrobial Therapy 2014</ref>==
Line 149: Line 158:
 
==Table Overview==
 
==Table Overview==
 
{{Clinically Relevant Bacteria}}
 
{{Clinically Relevant Bacteria}}
 +
 +
==Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae==
 +
*[[Meropenem-vaborbactam]]
 +
*[[Piperacillin/Tazobactam]]
  
 
==See Also==
 
==See Also==

Latest revision as of 19:16, 12 August 2018

Background

The majority of Klebsiella infections are caused by K. pneumoniae, followed by K. oxytoca.

Characteristics

  • Gram-negative
  • Lactose-fermenting
    • Grows pink on MacConkey agar
  • Urease positive

Differential Diagnosis

Causes of Pneumonia

Bacteria

Viral

Fungal

Parasitic

Antibiotic Sensitivities[1]

Category Antibiotic Sensitivity
Penicillins Penicillin G R
Penicillin V R
Anti-Staphylocccal Penicillins Methicillin R
Nafcillin/Oxacillin R
Cloxacillin/Diclox. R
Amino-Penicillins AMP/Amox R
Amox-Clav S
AMP-Sulb S
Anti-Pseudomonal Penicillins Ticarcillin R
Ticar-Clav S
Pip-Tazo S
Piperacillin S
Carbapenems Doripenem S
Ertapenem S
Imipenem S
Meropenem S
Aztreonam S
Fluroquinolones Ciprofloxacin S
Ofloxacin S
Pefloxacin S
Levofloxacin S
Moxifloxacin S
Gemifloxacin S
Gatifloxacin S
1st G Cephalo Cefazolin S
2nd G. Cephalo Cefotetan S
Cefoxitin S
Cefuroxime S
3rd/4th G. Cephalo Cefotaxime S
Cefizoxime S
CefTRIAXone S
Ceftaroline S
CefTAZidime S
Cefepime S
Oral 1st G. Cephalo Cefadroxil S
Cephalexin S
Oral 2nd G. Cephalo Cefaclor/Loracarbef S
Cefproxil S
Cefuroxime axetil S
Oral 3rd G. Cephalo Cefixime S
Ceftibuten S
Cefpodox/Cefdinir/Cefditoren S
Aminoglycosides Gentamicin S
Tobramycin S
Amikacin S
Chloramphenicol I
Clindamycin R
Macrolides Erythromycin R
Azithromycin R
Clarithromycin R
Ketolide Telithromycin R
Tetracyclines Doxycycline I
Minocycline I
Glycylcycline Tigecycline S
Daptomycin R
Glyco/Lipoclycopeptides Vancomycin R
Teicoplanin R
Telavancin R
Fusidic Acid R
Trimethoprim I
TMP-SMX I
Urinary Agents Nitrofurantoin I
Fosfomycin S
Other Rifampin R
Metronidazole R
Quinupristin dalfoppristin R
Linezolid R
Colistimethate S

Key

  • S susceptible/sensitive (usually)
  • I intermediate (variably susceptible/resistant)
  • R resistant (or not effective clinically)
  • S+ synergistic with cell wall antibiotics
  • U sensitive for UTI only (non systemic infection)
  • X1 no data
  • X2 active in vitro, but not used clinically
  • X3 active in vitro, but not clinically effective for Group A strep pharyngitis or infections due to E. faecalis
  • X4 active in vitro, but not clinically effective for strep pneumonia

Table Overview

Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae

See Also

References

  1. Sanford Guide to Antimicrobial Therapy 2014