Levamisole toxicity

Revision as of 03:36, 29 October 2014 by Rossdonaldson1 (talk | contribs) (See Also)

Background

  • an antihelminthic and immunomodulator belonging to a class of synthetic imidazothiazole derivatives that has been withdrawn from the U.S. and Canadian markets, due to the risk of serious side effects
  • Increasingly used as a cutting agent in cocaine sold around the globe
  • Results in Levamisole induced necrosis syndrome[1]

Clinical Features

  • agranulocytosis
    • neutropenia
  • levamisole induced necrosis syndrome
    • Necrotic patches anywhere on skin (especially ears and legs)

Differential Diagnosis

Workup

Management

Disposition

See Also

External Links

Sources