Difference between revisions of "Local anesthetic systemic toxicity"

(Created page with "==Background== *Complication of lidocaine injection (accidental into systemic circulation) **0.2% of nerve blocks *Occurs within minutes of injection **75% occuring within 5 minu...")
 
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**Respiratory arrest
 
**Respiratory arrest
 
*Cardiovascular
 
*Cardiovascular
 +
**First excitation
 +
***Tachycardia
 +
***Ventricular dysrhythmia
 +
***Hypertension
 +
**Followed by depression
 +
***Bradycardia
 +
***Conduction block
 +
***Asystole
 +
 +
===Management===
 +
*Lipid emulsion
 +
**1.5 mL/kg bolus over 1 minute
 +
**Then, 15 mL/kg per hour x 20-minute infusion
 +
 +
==See Also==
 +
[[Lidocaine Toxicity]]

Revision as of 11:09, 15 July 2013

Background

  • Complication of lidocaine injection (accidental into systemic circulation)
    • 0.2% of nerve blocks
  • Occurs within minutes of injection
    • 75% occuring within 5 minutes

Diagnosis

  • CNS symptoms
    • Agitation
    • Auditory changes
    • Metallic taste
    • Seizures or drowsiness
    • Coma
    • Respiratory arrest
  • Cardiovascular
    • First excitation
      • Tachycardia
      • Ventricular dysrhythmia
      • Hypertension
    • Followed by depression
      • Bradycardia
      • Conduction block
      • Asystole

Management

  • Lipid emulsion
    • 1.5 mL/kg bolus over 1 minute
    • Then, 15 mL/kg per hour x 20-minute infusion

See Also

Lidocaine Toxicity